Modulatory effects of neuropeptides on pentylenetetrazol-induced epileptic seizures and neuroinflammation in rats
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چکیده
منابع مشابه
Effect of berberine on pentylenetetrazol-induced seizures in rats
Objective: Antiepileptic drugs (AEDs) that are usually used for treatment of epilepsy have substantial side effects and about 30% of patients continue to have seizures with current AEDs therapy. Some herbs which traditionally used in the management of seizures of many rural areas of the developing countries have shown anticonvulsant activity in modern pharmacological bioassays. The aim of the p...
متن کاملMontelukast Inhibits Pentylenetetrazol-Induced Seizures in Rats
BACKGROUND Montelukast is an antiinflammatory drug with an antioxidant property. In this study, we aimed to reveal whether montelukast has a preventive effect against seizures and post-seizure oxidative stress in pentylenetetrazol (PTZ)-induced seizures in rats. MATERIAL AND METHODS Of the 48 male Sprague-Dawley rats used in the study, 24 were assigned to EEG recordings (group A) and 24 were ...
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چکیده اثر عصاره آبی سیر بر درد ناشی از آزمون فرمالین در موش صحرایی نر به کوشش نرگس اسکندری روزبهانی زمینه و هدف: گیاه سیر از خانواده لیلیاسه و گونهallium sativum بومی آسیای میانه بوده و از دوران ،باستان تاکنون به خواص درمانی متفاوت آن مثل: کاهندگی قندخون، کلسترول خون، فشار خون، اثرات مفیدآن بر دستگاه قلبی عروقی و بیماریهای انعقادی خون، اثرات آنتی اکسیداتیو، درمان بیماریهای تنفسی وگوارشی، ا...
15 صفحه اولEffect of berberine on pentylenetetrazol-induced seizures in rats
Objective: Antiepileptic drugs (AEDs) that are usually used for treatment of epilepsy have substantial side effects and about 30% of patients continue to have seizures with current AEDs therapy. Some herbs which traditionally used in the management of seizures of many rural areas of the developing countries have shown anticonvulsant activity in modern pharmacological bioassays. The aim of the p...
متن کاملAnticonvulsive and antioxidant effects of pioglitazone on pentylenetetrazol-induced seizures in mice
Introduction: Epilepsy is a neurological disorder caused by uncontrollable discharge of neurons in the brain. After a seizure oxidative stress play an important role in the oxidative neuronal damage. In this study, we evaluated the anticonvulsant and antioxidant effects of pioglitazone, a PPAR-γ agonist that is used in type2 diabetes, on pentylenetetrazol-induced seizure in mice. Methods: In t...
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ژورنال
عنوان ژورنال: Revista da Associação Médica Brasileira
سال: 2019
ISSN: 1806-9282,0104-4230
DOI: 10.1590/1806-9282.65.9.1188